The importance of integrating multiple genomics information has been well recognized by the research community.
Abaca has a high potential to substitute glass fibres in multiple automotive parts and is currently well recognized as a material for paper products.
Occurrence of multiple cases in a single family is well recognized and different series have shown prevalence of familial PBC ranging from 1.33% to 5.5%.
Also as multiple co-morbidities accrue with age, it is well recognized that these can impact safety driving.
Our findings identify respiratory deficiency due to mtDNA deletions as a potentially important pathomechanism in MS. Clonally expanded multiple deletions of mtDNA causing respiratory deficiency are well recognized in neurodegenerative disorders and aging.
To this end, the 1.3-3 fold increased risk for multiple morbidities including cancer in diabetes is now well recognized [ 36, 37] and support the frequent co-occurrence of hypoglycaemia, CKD and non-CVD deaths in our analysis.
The importance of sampling multiple genes when attempting to reconstruct species phylogenies is well recognized [ 18].
In addition, dyslipidaemia is well recognized as a complex trait caused by multiple environmental factors and the interaction of genetic and environmental factors.
LRRK2 is a complex 286 kDa protein that contains multiple well-recognized domains, including (in order, from amino to caboxyl terminus): LRR, Ras of complex (ROC), carboxyl-terminus of ROC (COR), kinase and WD40 domains (Figure 1A).
Caloric Restriction - Calorie restriction is perhaps the most well recognized anti-aging therapy, and exerts this effect in multiple ways [ 13].
Deregulation of the IGF system is well recognized as a key contributor to the progression of multiple cancers including BC. Binding of IGFBP1 prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
