Physical activity conveys multiple well established health benefits including decreased rates of coronary artery disease [ 1- 3], hypertension [ 4, 5], non-insulin dependent diabetes mellitus [ 6], osteoporosis [ 7], colon cancer [ 8], anxiety and depression [ 9, 10], as well as decreased risk of overall mortality [ 1].
We used the index of multiple deprivation, a well established method of assigning socioeconomic characteristics based on area of residence.
Furthermore, AP1 shares a biological process (GO: 0003700) with FLC, and its role in integrating signals from multiple pathways is well established (Mouradov et al. 2002).
While American officials say the withdrawal matches the latest counterinsurgency doctrine's emphasis on protecting Afghan civilians, Afghan officials worry that the shift of troops amounts to an abandonment of territory where multiple insurgent groups are well established, an area that Afghans fear they may not be ready to defend on their own.
Prudential analyst Jason Zhang said approval was widely expected as its effectiveness in treating multiple myeloma had been well established and used as an off-label treatment by physicians.
In contrast to the upfront setting in which the role of high-dose therapy with autologous hematopoietic cell transplantation (HCT) as consolidation of a first remission in patients with multiple myeloma (MM) is well established, the role of high-dose therapy with autologous or allogeneic HCT has not been extensively studied in MM patients relapsing after primary therapy.
The results of these pairwise comparisons are used to train an SVR model that predicts PFM-similarities which are quantified using the well established multiple alignment based PFM similarity score MoSta [36].
The importance of telomerase in multiple myeloma (MM) is well established; however, its response to bortezomib has not been addressed.
As is well established, multiple families contain mitochondrial target sequences (e.g., CYP12, CYP315, and CYP49), and they all fall within a deeper monophyletic group.
For differentiation of bacterial isolates several VNTR loci are combined in a Multiple Locus VNTR Analysis MLVAa), a well established tool for epidemiological studies of bacteria with highly fit clonal dominance [ 40- 44, 44, 58].
"It's well established in multiple myeloma that survival and response rates have a statistical correlation," says Barry Greene Barry Greene, general manager of oncology at Millennium.
