Sentence examples for multiple weekly dosing from inspiring English sources

Modest accumulation was observed upon multiple weekly dosing at 1.5 to 5 mg/kg SC or IV [ 14].

To validate this hypothesis and the therapeutic potential of the LNA ASO, a multiple dose study with weekly dosing of 5 mg/kg of the 13-mer LNA antisense oligonucleotide was conducted.

Interestingly, we found that alloantigen-induced proliferation of CD4+ T-cells obtained from rats that were subjected to multiple weekly DST increased in a dose-dependent fashion to more than 2 3 fold when compared to naïve CD4+ T-cells (Fig. 2B).

Multiple phase I and II clinical trials have established that standard weekly dosing of cetuximab or trastuzumab in humans achieves trough serum concentrations that are usually above 50 μg/ml [ 37, 38, 40- 42].

The MTD of weekly cabazitaxel was 12 mg/m and the recommended weekly dose was 10 mg/m.

Automated analysis of QC measurements was deemed necessary for implementing multiple, weekly measurements for PET/MR.

Q4W, monthly dosing; QW, weekly dosing.

With weekly dosing of oral ixazomib in relapsed or refractory MM, there was a dose-proportional increase in plasma exposure with a terminal half-life of 4 12 days after multiple dosing.

This has led to weekly dosing in clinical trials.

In conclusion, once weekly dosing of ganetespib is well tolerated.

Preliminary results from an ongoing phase IA/II dose escalation study, with one arm receiving three times weekly dosing and the other three times alternate weekly dosing.