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Mixed infections with multiple virus types can lead to reassortment and may have a significant role in virus evolution.
Recently, a new molecular biology-based microbial detection method for rapid identification of multiple virus types in one specimen has been developed.
New assays using multiplex reverse transcriptase polymerase chain reactions (MRT-PCR) are available allowing for relatively rapid detection of multiple virus types and simultaneous comparison of patient characteristics, symptoms, severity of illness and productivity across multiple viruses.
In single analyses containing multiple virus types, the microarray was able to identify specific viruses among pathogens that produce similar symptoms, and to discriminate between variants of different origins.
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Attempts have been made by others to address this question by including multiple respiratory virus types [ 24], and their results point toward a relatively conserved nature of the host response to viral infection.
Multiple infections at different times with different virus types may cause severe disease.
Experience with BTV suggests that they are also prone to cross-reactions between types, particularly in areas where multiple virus serotypes are co-circulating [58], [59].
Our persistence analyses revealed high turnover rates but also the presence of several virus types in the populations during multiple years of the study.
Analysis of multiple inoculated samples revealed a different focus of the detected virus types by the three assays.
Overall, although in any other hantavirus outbreaks, multiple virus introductions to humans from the environment are possible, clusters like type B are the exception.
The virus types which cause warts are not the types which cause cancer though.
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