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Exact(39)
Therefore, the cumulative results of detailed analyses suggested that four subjects A, D, OJ, and QP were infected with multiple viral variants, while multiplicity of HIV-1 transmission in one subject, PO, remained inconclusive.
We developed two computer-driven methods for improving epitope-driven HIV vaccines: the Epi-Assembler, which derives representative or "immunogenic consensus sequence" (ICS) epitopes from multiple viral variants, and VaccineCAD, which reduces junctional immunogenicity when epitopes are aligned in a string-of-beads format for insertion in a DNA expression vector.
Transmission of multiple viral variants is associated with faster disease progression [10] [12].
All cases that were identified as transmission of multiple viral variants or "undetermined" (implying that transmission of multiple viral variants cannot be excluded) were correctly rejected by the Poisson-Fitter through the GOF test.
This approach enables the resolution of transmission of single or multiple viral variants in nearly all analyzed samples.
Therefore, the recombination analysis supported transmission of multiple viral variants in 3 of 5 subjects: A, OJ, and QP.
Similar(21)
For example, we decomposed the effect of rs2395029 (a marker of HLA-B*57 01 HLA-B*57 01he effects on the multiple VLral amino acid varianto thet areffectsiated with that SNP.
In case of transmission of multiple or closely related viral variants, the selection of one viral population over time was not uncommon.
Although no rupintrivir-resistant viruses have been reported previously, we could select such a variant during multiple viral passages in the presence of the drug.
In contrast to the cross-sectional studies, the current study focuses on multiple time points assuming that functionally relevant viral variants should be detectable in a set of longitudinal samples even with a relatively small number of viral sequences per time point.
These processes are especially significant in long-term persistent infections where multiple viral genotypes co-replicate in a single host, generating abundant genotypic variants, some of which may possess novel host-colonizing and pathogenicity traits.
More suggestions(15)
multiple viral epitopes
multiple viral infections
multiple parental variants
multiple viral oncoproteins
multiple viral antigens
multiple viral genomes
multiple viral vectors
multiple viral proteins
multiple viral siRNAs
multiple viral families
multiple viral targets
multiple causal variants
multiple viral haplotypes
multiple viral genes
multiple viral species
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