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Despite the frequent observation of masking of HIV-1 neutralization epitopes, its extent has not been previously systematically assessed either for multiple epitopes presented by individual viruses or for individual epitopes across multiple viral strains.
They believe the virus had already jumped to humans at this time; a later invasion would require that multiple viral strains entered people before spreading from person to person--a scenario Korber calls very unlikely.
The presence of multiple viral strains within a host permits inter- and intra-subtype recombination, which increases global HIV diversification [5], [21], [22], [27] [29].
The use of CTL epitopes, especially conserved ones shared by multiple viral strains, and identification of HLA class I (HLA-I) binding immunogenic peptides, might therefore be basis for a robust vaccine strategy against emerging influenza epidemics.
The threat posed by emerging strains of influenza is unpredictable and varies among countries, as evidenced by the recent swine origin H1N1 pandemic, highlighting the need for improved vaccines that can confer broad protection against multiple viral strains and various influenza A subtypes.
We observed multiple viral strains that did or did not contain an insertion of 14 amino acid residues in the PTAP domain of p6 gag.
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To further assess the overall contribution of each antimicrobial and anti-HIV IgG for protection against multiple HIV viral strains, the percent reduction in HIV infection of TZM-bl cells for each isolate was divided into quartiles, and a score assigned to each quartile.
Van Vuuren et al. [13] studied the effect of cross protection on HLB of Africa by vaccinating multiple citrus recession viral strains.
Our knowledge of HCMV protein profiles has so far relied on a literature complicated by the use of multiple different laboratory-adapted viral strains, different cell types, and variable infection conditions (Ma et al., 2012).
Multiple viral population bottlenecks within R5 strains preceded the bottleneck leading to appearance of X4 variants in both individuals (Figure 4).
The human outbreaks consisted of multiple simultaneous epidemics caused by different viral strains, and each epidemic resulted from the handling of a distinct gorilla, chimpanzee, or duiker carcass.
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multiple viral particles
multiple viral pathogens
multiple viral antigens
multiple viral vectors
multiple viral proteins
multiple viral siRNAs
multiple viral channels
multiple viral coinfections
multiple viral families
multiple viral genotypes
multiple viral subtypes
multiple viral harvests
multiple viral lineages
multiple viral haplotypes
multiple viral sequences
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