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Correct assembly and budding of influenza virus requires cooperative action by multiple viral proteins with the lipid bilayers and genomic RNA as well as host proteins [45], [46].
The distribution of higher diversity associated with suppression of viral titers across multiple viral proteins suggests that there are many ways lesions to the HCV genome could reduce the efficacy of these suppressive functions.
Influenza A virus regulates apoptosis in several ways through multiple viral proteins with both pro- and anti-apoptotic activity [ 148].
This indicates that these host miRNAs have potential for regulating the expression of multiple viral proteins namely, PB1, PB1-F2, aN40N40.
Our approach provides a method to analyze the distribution of RNA and multiple viral proteins within virions simultaneously, using both conventional and localization microscopy.
Their efficiency and robustness depends on the selection of an invariant segment that is independent of viral mutations or relies on the statistical advantage based on targeting multiple viral proteins.
Similar(51)
Albeit the assembly process is not yet completely understood for tombusviruses or other -strand RNA viruses, it is likely that multiple viral protein - host protein and viral RNA - protein interactions as well as protein - subcellular membrane interactions have to take place for successful replicase assembly [24], [58].
Interference of multiple viral protein functions by a single-batch dsRNA should also be an ideal approach for RNAi-mediated fighting against viruses, especially the large and complicated WSSV.
VLPs result from the self-assembling of single or multiple viral capsid proteins and have been shown to be safe and efficacious in humans.
More recent immuno-EM analyses revealed that the intranuclear crystals reacted with anti-hexon, anti-penton base and anti-fiber knob antibodies [43], as well as with protein kinase CK2 and dsRNA-activated protein kinase PKR antibodies, leading to the assumption that multiple viral and cellular proteins were components of the crystals [44].
Ad has a strictly regulated infection cycle where multiple viral and cellular proteins interact to complete the viral replication program to generate infectious virus particles.
More suggestions(15)
multiple viral epitopes
multiple viral infections
multiple soluble proteins
multiple viral particles
multiple viral transcripts
multiple viral variants
multiple viral oncoproteins
multiple viral pathogens
multiple viral antigens
multiple viral vectors
multiple viral genomes
multiple viral siRNAs
multiple viral families
multiple viral genes
multiple viral haplotypes
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