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Repeated propagation at intermediate frequency suggests that transmission of multiple viral haplotypes may be common.
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Since consistent differences in peak height on both strands likely reflect variation in the abundance of viral haplotyes, we used this information to infer viral haplotypes.
For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy.
Multiple viral vectors have been studied.
The elements of A L are synonymously referred to as viral haplotypes, genotypes, or strains.
The frequencies of viral haplotypes are determined by evolutionary parameters, including mutation rate and fitness.
No multiple viral infections and no bacteria were detected.
The posterior fitness distributions allowed for differentiating viral haplotypes from each other, for determining neutral haplotype networks, in which no haplotype is more or less credibly fit than any other, and for detecting epistasis in fitness landscapes.
The compositions of the viral populations had been inferred with the probabilistic viral haplotype reconstruction tool QuasiRecomb (Töpfer et al. 2013).
The phylogenetic history of these extended haplotypes was examined using a haplotype network [20], since network approaches account for the persistence of ancestral haplotypes, the existence of multiple descendant haplotypes, recombination, and low levels of sequence variation [21].
The study found multiple TRAP haplotypes in most birds.
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