Sentence examples for multiple viral and from inspiring English sources

The targeting of multiple viral and host cell elements simultaneously by RNAi could increase the potency of antiviral gene therapies.

BRDC is a multi-factorial disease with environmental conditions interacting with multiple viral and bacterial pathogens to produce severe respiratory illness.

Ad has a strictly regulated infection cycle where multiple viral and cellular proteins interact to complete the viral replication program to generate infectious virus particles.

There are multiple viral and host restrictions, which uniquely direct EBV's susceptibility to humans including the human surface receptor CD21 and HLA class II molecules, which are crucially involved in virus adsorption and entry [11], [12].

More recent immuno-EM analyses revealed that the intranuclear crystals reacted with anti-hexon, anti-penton base and anti-fiber knob antibodies [43], as well as with protein kinase CK2 and dsRNA-activated protein kinase PKR antibodies, leading to the assumption that multiple viral and cellular proteins were components of the crystals [44].

If extreme weather events become increasingly frequent owing to global climate change, the consequent synchronization of proliferating pathogens or their vectors may cause disease to become a major threat to historically stable populations that had previously coexisted with multiple viral and parasitic pathogens.

CRISPR/Cas9 can efficiently target single and multiple viral infections and confer plant immunity.

60 The blood-borne contagious risk has been reduced by multiple viral inactivation and removal steps including cryoprecipitation, chromatography, and pasteurization; nanofiltration is added to a recently US Food and Drug Administration (FDA -approved C1-INH concentrate.

Cocktails of mAbs and bispecific constructs can be used to simultaneously target multiple viral epitopes and to overcome issues of neutralization escape.

Three subjects in the NJ tree (Fig. 1; subjects D, OG, and OW) and three subjects in the ML tree (Fig. 2; subjects OG, OW, and PP) demonstrated extended length of branches suggesting transmission of multiple viral variants, and highlighting the necessity of using alternative methods for inferring phylogenetic trees.

A major goal of developing anti-HIV-1 RNAi therapy is to target HIV-1 in a manner that prevents viral escape; such strategies may include targeting multiple viral sites and endogenous host factors that are required for HIV-1 infection and replication.