Sentence examples for multiple vesicle trafficking from inspiring English sources

Together these studies suggest that aSyn causes defects in multiple vesicle trafficking steps.

Atg6 (Beclin 1 in mammals) is a core component of the Vps34 PIII (III) complex, which promotes multiple vesicle trafficking pathways.

One larger cluster, cluster 14 with 26 genes enriched with GAAATT motifs, was found to contain CBP60g alongside multiple vesicle trafficking components, including some shown to be important for SA homeostasis [ 40].

This lipid kinase complex is involved in multiple vesicle trafficking processes in yeast in addition to autophagy, namely, endosome maturation and biosynthetic transport to the vacuole, the yeast equivalent of lysosomes [ 7].

As Vps34 and Vps15 have been shown to mediate multiple vesicle trafficking events and cell polarity [ 14– 18], we assumed that Atg6, as a component of the PI3K (III) core complex should also mediate such processes.

Lysosomes also serve as a common endpoint for multiple vesicle-based trafficking systems [ 32].

This is consistent with the idea that AtRabD2b and AtRabD2c are required for vesicle trafficking in multiple cell types, and that the highest demand for this process may be in pollen and pollen tubes, in order to optimally support the large secretory requirement of these very rapidly elongating cells.

Although varying cellular and biological functions were represented by genes in these genetic networks, the presence of multiple genes functioning in inflammation (Fig. 6A), vesicle trafficking (Fig. 6A) and nuclear receptor signaling (Fig. 6A and 6B) was particularly significant.

OPTN has been shown to localise to the Golgi complex in multiple cell types and play an important role in vesicle trafficking through the formation of complexes with binding partners such as Rab8, HTT and myosin VI.

17, 18 Dysferlin has multiple roles in skeletal muscle including sarcolemmal membrane repair, 16, 19, 20 vesicle trafficking, 21 t-tubule structure and function 22 and endocytosis.

Rho GTPases contribute to multiple cellular processes that could affect cancer progression, including cytoskeletal dynamics, transcriptional regulation, vesicle trafficking, apoptosis, cell cycle progression and migration [ 32].