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The Iranian drone program, like its Western counterparts, is secretive and replete with multiple variants that have different ranges and capabilities.
This may be due to pleiotropy of variants, to close proximity and linkage of multiple variants that have an impact on different traits, or to long-range gametic phase disequilibrium caused by cross-trait assortative mating.
Recent genome-wide association studies have identified multiple variants that confer risk of type 2 diabetes mellitus (DM).
Mutations in key genes that affect hematological parameters have important phenotypic consequences, including multiple variants that affect susceptibility to malarial disease.
Further studies will need to consider strategies to assess the role of multiple variants that occur in < 1 in 1000 individuals.
Unlike tetanus toxin, which appears uniform from strain to strain, bont gene sequence comparisons have identified multiple variants that are recognized as serotypes and subtypes.
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The likelihood that the mosquito genome contains multiple histone H1 gene variants is consistent with the multiple H1 variants that have been described in Chironomus [ 9- 11] and eight histone H1 subtypes that have been described in mammals [ 14, 15].
Although typical meningiomas have characteristic imaging features, there are multiple atypical variants that may be diagnostically challenging and the value of MRI in predicting WHO grades in meningiomas is limited.
Hereditary predisposition to cancer is sometimes due to a single high-risk genetic change, like a mutation in the BRCA1 or BRCA2 genes for breast cancer, but most of the time, the disease is the result of multiple gene variants that add up, environmental risk factors, and a big element of chance.
It is suspected that the sporadic forms of neurodegenerative disorders are caused by multiple genetic variants that individually make relatively weak contributions to risk.
Approximately ∼10% of the gene descriptors in the array represent multiple splice variants that can also be deduced from the nucleotide sequences (Table S3).
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