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The main lesson from our validation process is the need for multiple validation strategies, including empirical validation.
The developed quantitative models have been subjected to extensive statistical tests employing multiple validation strategies from which acceptable results have been reported.
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Compared with the multiple scale validation strategy, the dataset of WSN albedo "truth" at the coarse-pixel scale reveals a good quality both in stability and continuity.
A multiple random validation strategy has been suggested to combat this problem [ 27].
To estimate sensitivity and specificity of the classifiers, we combined nearest centroid classification with a multiple random validation strategy, as in [ 21].
In an extensive additional analysis we investigated the performance of classifiers that include a larger number of metabolites using a multiple random validation strategy.
This standardization processing includes multiple validation and normalization steps.
The adopted stepwise methodology included multiple validation checks with experts.
However, the different experimental designs and validation strategies preclude direct quantitative comparison.
However, such studies are typically conducted on different datasets, using different validation strategies, and different metrics.
Two different validation strategies were used to address practical situations.
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