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This defective actin remodeling would have multiple undesirable effects in a neuron, such as synaptic and dendritic dysfunction, leading to the initial synaptic dysfunction and changes in spine density observed in the early stages of HD.
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However, the use of these promoters has multiple potentially undesirable effects on metabolism and host gene transcription and, importantly, can also lead to a slow growth rate and/or a high cost incompatible with biotechnological applications, making them suboptimal.
These results suggested that the higher dose of genistein can produce several undesirable effects by affecting multiple cellular pathways.
133 Studies in animal models are required to test vibralactone's effectiveness and possible undesirable effects.
Negative interest rates could have widespread undesirable effects across the economy.
The undesirable effects of radiation therapy are divided into acute and late effects.
Half of the group, however, did not experience these undesirable effects.
Deforestation, cultivation, and guano mining have had undesirable effects on terrestrial ecosystems.
Streaking and blotching are undesirable effects.
Moreover, different undesirable effects have been attributed to this compound.
Drugs and their metabolites often produce undesirable effects.
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