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The present method could become a valuable tool to quantify dissociated responses on multiple tumour sites, e.g. primary tumour and metastatic nodes, provided that all the regions of interest are selected.
Imaging is also minimally invasive or non-invasive, can be repeated and can cover multiple tumour sites.
It is therefore not limited to characterizing one or a few target lesions, but can evaluate multiple tumour sites at the same time.
Imaging is non-invasive and can assess multiple tumour sites, which is an important consideration given the known heterogeneity of expression of many histological markers.
Imaging correlates for genetic markers would potentially provide an adjunct to histologic assessment by enabling simultaneous evaluation of the whole tumour and multiple tumour sites and by providing an indication of mutation status when tissue sampling has failed.
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Repeat aspirates may be performed to assess progress following treatment, or multiple suspected tumour sites may be aspirated to assist staging.
Furthermore, metastasis from half of the patients studied underwent polyclonal seeding with the transfer of multiple tumour clones between metastatic sites.
This may have potential clinical utility as whole-body MRI is currently being evaluated as a staging modality in different tumour sites such as multiple myeloma.
In 15 rats, multiple tumour growths were observed at 1 4 sites in the body, including tumours in the left and right thoracic chest (C) and the femoral site (F) for groups II, III, and IV (rats receiving DMBA).
We argue that much will be learned through the acquisition of multiple tumour samples from different regions of the primary and metastatic tumour sites and at sequential time points in the disease course, including before, during therapy and at disease progression, to study the changing nature of tumours over time.
The Fragile Histidine Triad gene, encompassing the FRA3B fragile site at chromosome 3p14.2, is a candidate tumour suppressor gene involved in multiple tumour types including colorectal carcinomas.
More suggestions(15)
multiple tumour characteristics
multiple tumour tissues
multiple tumour deposits
multiple tumour localisations
multiple tumour samples
multiple tumour models
multiple tumour probes
multiple tumour implants
multiple tumour sections
multiple tumour settings
multiple tumour regions
multiple tumour lesions
multiple tumour outcomes
multiple tumour types
multiple infection sites
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