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However, CT and MRI revealed multiple tumors with ring enhancement.
The axial (c) and coronal view (d) of the thyroid gland on contrast-enhanced computed tomography showed heterogeneously enhanced multiple tumors with microcalcifications.
HCC often presents with multiple tumors, with only approximately 25% of tumors originating from de novo lesions.
In other words, multiple tumors with smooth borders would more likely represent separate primaries, and tumors with irregular borders would more likely represent intraglandular metastasis [ 1].
Radiotherapy is an important modality in tumor combinational treatment and is used for treating multiple tumors with good therapeutic effects [ 1].
Ishizawa et al. demonstrated that partial hepatectomy provided survival benefits for patients with multiple tumors with Child-Pugh class A cirrhosis[ 25].
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11 Their selection criteria are similar to ours, but slightly more patients with multiple tumors were included than patients with CRC below the age of 50 years.
Our results supported that patients with HCC with major vascular invasion had a significantly poorer prognosis than those with multiple tumors more than 5 cm, those with invasion of adjacent organs, or those with perforation of visceral peritoneum.
Early detection is very important for RFA because large and multiple tumors are associated with poor prognosis [14].
In case of multiple tumors per patient with different histology, or multiple histological types within one tumor, each type was counted.
Meningiomas may occur either as familial tumors in two distinct disorders, familial multiple meningioma and neurofibromatosis 2 (NF2), or sporadically, as either single or multiple tumors in individuals with no family history.
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