Sentence examples for multiple tumor suppressor from inspiring English sources

Au, S. L. et al. Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis.

In conclusion, HACE1 is another potent tumor suppressor gene located within the 6q21 region, and loss of function of multiple tumor suppressor genes within 6q21 may be a critical determinant of NK cell lymphomagenesis.

These data suggest that overexpression of various DNA methyltransferases might represent a critical event responsible for the epigenetic inactivation of multiple tumor suppressor genes, leading to the development of aggressive forms of sporadic breast cancer.

Genetic, epigenetic, or functional inactivation of multiple tumor suppressor genes is a hallmark of human cancers [1].

Aberrations of either region were detected in more than 90% of the studied tumors suggesting they harbor multiple tumor suppressor genes (TSG) [5], [6], [7].

To test whether the hypermutation feature is a characteristic only of the RASSF1A gene or a more general phenomenon, we similarly analyzed the recently identified multiple tumor suppressor gene RBSP3 located in AP20, 3p21.3 telomeric region [10].

Xu, J. et al. Gain of function of mutant p53 by coaggregation with multiple tumor suppressors.

The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin.

Baron V, Adamson ED, Calogero A, Ragona G, Mercola D. The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin.

APOE4 AD alleles activate multiple tumor suppressors, tumor inducers and negative regulator of cell growth or repressors that may lead to increased cell arrest, senescence and apoptosis.

These results are consistent with a model for disease progression in MDS that includes the alteration of multiple tumor suppressors in hematopoietic stem or progenitor cells.