Sentence examples for multiple trials that from inspiring English sources

Compared to the multiple trials that have been undertaken to actively generate systemic immune responses specific for PrP in wt mice, our results show the best protection.

In the context of rare diseases, the advantage of the cmRCT design to conduct multiple trials that draw participants from the same patient cohort is particularly important given the difficulty of recruiting a sufficiently large patient group for any single trial.

Then treatment A can be used as a common comparator to adjust the indirect comparison of treatment B and C: d BC Ind = d AB − d AC Its variance is: V a r d BC Ind = V a r d AB + V a r d AC When there are multiple trials that compared treatment A and B or treatment A and C, results from individual trials can be combined using fixed-effect or random-effects model.

Formulae to do this are uncommon because they require primary data from multiple randomized trials that measure both the surrogate and clinical outcome.

However, to control for multiple testing, trials that are not stopped early generally require larger sample sizes compared with similarly designed non-sequential trials.

Furthermore, some recent review articles that performed meta-analysis of multiple trials reported that intensive glycemic control does not inevitably result in a reduction of cardiovascular events and mortality [ 31, 32].

The final distribution appeared to be systematically invariant with respect to the choice of initial random coordinates over multiple trials, suggesting that the global minimum of H was reached in each case.

The multiple trials mean that individual control rats almost invariably perform above chance with short retention delays [67].

For future pharmacogenetic research, the pre-competitive participation of pharmaceutical companies, which could contribute DNA samples and outcomes garnered during multiple clinical trials that compare proprietary compounds with generic drugs, may be crucial.

This is because the proportion of sites under positive selection may simply be a sum of multiple independent Bernouli trials that each determine whether or not a given site is under positive selection), divided by the total number of sites.

The International Chiropractors Association published 'Best Practices and Practice Guidelines' in which they summarized multiple randomized controlled trials that used SMT or mobilization as the primary form of care and NRS or visual analog scale (VAS) as outcomes [ 51].