In order to compare the discriminative power of the associative memory test and the item memory test with multiple trials for detecting aMCI from normal aging, the ROC curve analysis was used separately for the first trial, the third trial, and the aggregate total score on trials 1 3 in both tests (see Figure 4).
With the existing different HIV subtypes, multiple trials are needed from different geographical sites.
A caveat is that it cannot be proved whether this assumption applies to each individual trial as the results from Experiment 1a reflect cumulative data from multiple trials, while the objects, by necessity, were different from those in Experiment 1b.
Four genomic regions with QTL identified from multiple trials (QTL3.1, 5.1, 5.3, and 8.1) lacked significant QTL from the two trials carried out under the shortest photoperiod in the growth chambers, but variation due to different photoperiods and other environmental effects in the trials may be confounded.
Uncontrolled multiple trial data from over 300 SLE patients have been published from one centre suggesting a positive outcome; one single centre comparative study in 172 RA was positive.
Both were meta-analyses, in which information from multiple trials are combined into a single data set.
But meta-analysis, though a respectable technique for extracting information from multiple trials of particular treatments too small to be of individual significance, is being stretched to the limit here.
Evidence from multiple trials demonstrates the efficacy of prophylactic β-blocker, amiodarone, and corticosteroid administration in reducing the incidence of postoperative atrial fibrillation.
Use of these definitions at the FDA has enhanced the ability to aggregate data within and across medical product development programs, conduct meta-analyses to evaluate cardiovascular safety, integrate data from multiple trials, and compare effectiveness of drugs and devices.
(A meta-analysis involves pooling the results from multiple trials on the same subject.
