In the future, we plan to release comprehensive reports on multiple trials conducted under the same controlled environment, which will allow us to understand universal features of each model and to look for the intrinsic predictability of earthquake rupture processes.
1, 2 Multiple trials conducted over the past decade have failed to document the superiority of a variety of approaches compared with the standard doublet of a platinum (carboplatin or cisplatin) agent plus a taxane (paclitaxel or docetaxel).
The data used in the analysis were gathered across multiple clinical trials conducted during the clinical development program for ecallantide.
A meningococcal group A conjugate vaccine, PsA-TT (MenAfriVac), developed through the Meningitis Vaccine Project and manufactured by the Serum Institute of India, Ltd, was tested in multiple clinical trials conducted mainly in Africa.
Multiple controlled trials conducted in the United States addressed short or medium term effects of HRA and showed positive effects on health behaviour and uptake of preventative care in older persons, provided HRA was combined with a system of personal reinforcement (supplemental counselling by a physician, health educator, or other health professional) [ 3].
Multiple separate trials conducted as part of the Risk Evaluation and Education for Alzheimer's Disease REVEALL) study have shown that cognitively normal adults with an affected parent or sibling who learned of an increased genetic risk for AD are more likely than those at population risk or those receiving non-genetic risk assessments to report changes in putative AD-prevention behaviors [ 3, 4].
However, the behavior of Pdcl cKO mice was dramatically different when multiple trials were conducted.
Thus, if one considers the newly diagnosed patients each year, the barriers to enrollment, and the number of participants needed as multiple trials are conducted simultaneously, it is clear that the recruitment needs for AD clinical trials will remain a challenge that results in competition for eligible subjects.
A number of cultivars with stably low accumulation of either Cd or As in the grain were identified based on the trials conducted in multiple sites and seasons (Table 3).
Trials conducted over multiple sites tend to be large collaborations of implementing and research partners.
Clinical trials conducted by multiple groups have shown a potential benefit of cisplatin-based ACT for individuals with completely resected tumors, ranging from a 4-15 % survival benefit [ 5, 6].
