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When studies included multiple trial arms, data on each intervention arm compared with the usual care arm were included in meta-analyses.
However, this would have blown up the design to include multiple trial arms and large numbers of practices and patients, and turn it into an unfeasible experiment.
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Again this is due to the joint dependence of the multiple contrast estimates on common trial arms.
Standard testing services were available in both trial arms.
To determine likely contamination across trial arms.
The trial arms were well balanced.
Attrition between trial arms was similar.
One trial had three arms (Tomashek 2001 TNZ) and the remaining three trials had two trial arms.
Potentially eligible women were randomized into four trial arms: 1) blind hormone therapy arm, 2) blind placebo arm, 3) non-blind hormone therapy arm, 4) non-treatment arm.
With multiple outcomes of interest, the economic evaluation took the form of a cost-consequences analysis where the difference in costs experienced between the two trial arms is compared to the difference in all outcomes included in outcome evaluation.
Each session consisted of multiple trials in the radial-arm maze, one after the other, and lasted 20 min. Different randomized arm sequences were used on successive trials.
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CEO of Professional Science Editing for Scientists @ prosciediting.com