There are multiple treatment options for favorable-risk prostate cancer.
Randomized trials may need to accommodate multiple treatment options.
Vulvodynia is a poorly characterized condition with multiple treatment options that have been described as largely ineffective in research settings.
Opioid-dependent (OD) patients seeking treatment have multiple treatment options including abstinence-based and medication replacement therapies.
(Foster told me that his company "believes it is critical for physicians and patients to have multiple treatment options, including opioid analgesics," to help patients with acute and chronic pain get better and go back to work).
Multiple treatment options exist, offering different potential for symptom control at highly variable initial costs, but the relative value of these treatment options is unknown.
"We have a disease that's gone from having no treatments 20 years ago to having multiple treatment options," said Dr. Timothy Coetzee, the chief research officer at the National Multiple Sclerosis Society.
William Foster, a spokesperson for the Janssen Pharmaceuticals subsidiary of Johnson & Johnson, said that the company believes it is "critical for physicians and patients to have multiple treatment options, including opioid analgesics, to help people who need relief from acute and chronic pain," while also recognizing "the potential for misuse of opioid analgesics".
For these reasons, cost optimization of DNAPL cleanup needs to consider multiple treatment options and their associated costs while also gauging the influence of prediction uncertainty on expected costs.
The enrichment design is most appropriate when compelling preliminary evidence suggests treatment benefit in only certain marker-defined subgroups, the all-comers design is useful when preliminary evidence regarding treatment effects in marker subgroups is unclear, and adaptive designs have the most potential in the setting of multiple treatment options and multiple marker-defined subgroups.
OBJECTIVES: Multiple treatment options exist for concurrent posterior urethral trauma and pelvic fractures.
