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His possible salvation would come only from multiple, sometimes difficult, treatments that included an expensive new drug to stimulate platelet growth, chemotherapy to kill the antibodies he'd developed that kept attacking his own blood, drugs to treat his low blood pressure, and multiple transfusions of platelets and red cells just to keep him alive.
Conclusions: The multiple transfusions of RBC and TBP could have a negative effect on long-term HRQOL in patients in cardiogenic shock requiring cardio circulatory support.
Children who have undergone HSCT are at high risk of fluid overload due to voluntary intravenous hyperhydration, infusion of multiple antibiotics, veno-occlusive disease, and multiple transfusions of blood products.
Objectives: The aim of this study is to assess the influences between multiple transfusions of and long term Health Related quality of life (HRQOL) after cardiogenic shock that required VAD.
This suggests that multiple transfusions of the same patients occurred in the control group.
The most important analytical issue for our primary analysis is that of modelling multiple transfusions of varying transfusion donor ages.
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Of the remaining 3 patients, 1 received two transfusions (1 for hemorrhagic shock and 1 for anemia); 1 received multiple transfusions for shock, multiple trauma (fractures), as a postsurgical procedure, and for anemia; and 1 was transfused for postoperative hemorrhage.
Individual patients could contribute multiple transfusions to these analyses.
The definition of multiple transfusions included transfusion of different blood products, which is a reflection of current transfusion practice.
A total of 24 patients had multiple transfusions, 18 of whom had ≥ 5 days between transfusions and 6 of whom had ≤ 4 days between transfusions.
Excess iron, due to multiple transfusions (>20 units of packed red cells), is toxic through the production of free radicals derived from activated oxygen species, resulting in organ dysfunction and oxidative stress.
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