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The majority of mammalian genes produce multiple transcripts resulting from alternative splicing (AS) and/or alternative transcription initiation (ATI) and alternative transcription termination (ATT).
Any sites with multiple transcripts resulting in multiple annotations were annotated only once using the by-gene option in VEP [ 35].
Alternatively, these probes may contain conserved motifs and therefore the probes on the microarray will cross-hybridize to multiple transcripts resulting in the higher signal intensities observed on the microarray for these elements.
Preprocessing of the gene sets selected the longest protein-coding transcript of any gene annotated with multiple transcripts resulting in a nonredundant set of 1,363,300 protein-coding genes for subsequent orthology delineation analysis.
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In some species, multiple FAK transcripts resulting from alternative splicing and/or promoter usage have been characterized.
In addition to the mutually overlapped transcripts, the sequence reads are usually mapped to multiple nonoverlapping transcripts, resulting in ambiguous mapped loci.
We also showed multiple aberrantly spliced transcripts resulting from the activation of cryptic splice sites in exon 7, and encoding frame-shift proteins followed by premature truncation [10].
Several of them have been correlated with AML pathology (like the leukemia-associated factor RUNX3/ and2), are are known to have multiple transcript variants resulting from alternative splicing events (like ARHGAP4, EPHB6, MPG, PLXNB1, RUNX3 and SEC14L1; as indicated in NCBI GENE database).
By mapping the chromosome 8 HPV-genomic fusion transcripts onto the DNA sequence, we distinguished read-through and spliced transcripts resulting from the two independent HPV-18 genomic fragment copies, and we also detected multiple alternative splicing events (Fig. 5d).
Given that multiple transcripts can results from the single gene, the comparison of number of expressed genes to number of expressed transcripts should be made cautiously.
This indicates that those exonized transcripts resulted from Ds1 merely offering acceptors will not yield type I transcripts.
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