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The 107 genes (excluding Hsp70: see below) across the three genesets included 38 genes with multiple transcripts in D. melanogaster, for a total of 148 transcripts in the 107 genes.
Genes with multiple transcripts in the microarray were summed prior to ratio comparison.
Both proteins are encoded by multiple gene copies each represented by multiple transcripts in the K. brevis EST data.
Alternative splicing (AS) is a crucial mechanism in the generation of multiple transcripts in functional diversity from a single gene loci in eukaryotes.
However, we did not have enough information to accurately evaluate the actual reason for the multiple transcripts in each case, and accordingly, all the multiple contigs from the same gene were treated as independent contigs in this report.
Using zebrafish as an example, we present the development of RNAscope-based detection of multiple transcripts in whole-mount embryos, offering a procedure that is compatible with protein localization.
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The observed alterations in multiple transcripts involved in apoptosis in our studies are also consistent with this proposed mechanism of iodide-induced thyroid toxicity.
Some of the distal interactions were validated by siRNA knockdown experiments, including a locus involved in the regulation of multiple transcripts involved in the ER stress pathway.
As a result, around 50% of the genes presented multiple transcripts differing in the length of the UTRs, sometimes in the order of hundreds of nucleotides.
There were multiple transcripts involved in the metabolism of reactive intermediates that showed significantly different transcriptional behavior as a result of filarial worm infection, thus facilitating the return to homeostasis after a successful immune response.
Any sites with multiple transcripts resulting in multiple annotations were annotated only once using the by-gene option in VEP [ 35].
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