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Syp associates with multiple transcripts encoding key synaptic regulators, as well as many mRNAs encoding proteins of unknown function.
SOD2-deficiency had profound effects on transcription of genes involved in mitochondrial metabolism, with multiple transcripts encoding proteins involved in oxidative phosphorylation, ATP synthesis, TCA cycle and mitochondrial biogenesis down-regulated in Sod2-/ erythroblasts (figure 3).
CHMP2B cases show downregulation in multiple transcripts encoding proteins involved in the transport of cargoes along microtubules, suggesting impairments in axonal transport (KIF1A, KIF1C, KIF5C DYNLL21, DYNLL2 and DYNC1H1), a phenomenon that has been well documented in multiple neurodegenerative diseases, including a SOD1-mediated model of ALS [55].
Alternative splicing is emerging as a major molecular mechanism to extend the repertoire of functions produced by individual genes, through the expression of multiple transcripts encoding proteins with different biochemical and physical properties, and to diversify the regulation of their expression through alternative 5' and 3'UTRs.
Here, we found multiple transcripts encoding anthocyanidin glucosyltransferase and anthocyanin acyltransferase in the database.
Multiple transcripts encoding proteins involved in heat-shock were observed to be down regulated in Wolbachia-infected S2 cells.
Similar(47)
In rat, two functional genes are reported for S27; multiple transcripts encode each isoform and exhibit different tissue expression patterns [ 48].
Splicing is used by HIV-1 to produce multiple mRNA transcripts encoding various proteins [ 18].
The Septin 9 gene belongs to a class of GTPases involved in numerous cellular process [22].The gene has been shown to have multiple alternatively spliced transcripts encoding at least 5 characterized polypeptides designated v1 v5 [23], some of which have been associated with cancer.
For instance, 4-coumarate-CoA ligase is present redundantly in multiple copies, whereas transcripts encoding lycopene cleavage dioxygenase - an important component of the bixin biosynthetic pathway were not observed at all.
Therefore some probes lack specificity and the conventional probe sets do not always reflect current knowledge about the multiple individual transcripts encoded by the same gene.
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multiple unigenes encoding
multiple sequences encoding
multiple loci encoding
multiple transcripts representing
multiple cDNAs encoding
multiple transcripts resulting
multiple Unigenes encoding
multiple pathways encoding
multiple operons encoding
multiple data encoding
multiple promoters encoding
multiple genes encoding
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