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Instead, multiple transcripts are expressed at levels within the range of that observed within species.
Through alternative splicing, multiple transcripts are produced from a single mRNA precursor, widely expanding proteome diversity.
Similarly, multiple transcripts are observed for the Salmonella typhimurium ncRNAs CsrA, CsrB, MicA, and SraL, which were determined to be degradation intermediates [ 50].
694 oligonucleotides were designed, targeting 796 genes (several ORFs are multicopy and hence multiple transcripts are sampled by a single oligonucleotide in such cases).
For simplicity, multiple transcripts are present at the same concentration in this modified design, rather than each transcript at a different concentration.
We have shown that synthetic duplex RNAs with at least partial complementarity to multiple transcripts are capable of specific suppression of multiple target genes.
Similar(51)
Multiple transcripts were analyzed simultaneously for 40 cycles using an optimized qRT-PCR thermal profile.
Interestingly, when multiple transcripts were detected for a CG, alternative splicing was observed in 61% of the cases.
To create exon skip junctions in silico, a gene containing multiple transcripts was first reduced to a single 'full length transcript' (Fig. 2a) as described in Materials and Methods.
Reads aligned to multiple transcripts were not considered for estimating the depth of the transcript.
Reads that had equal-quality matches to multiple transcripts were excluded.
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