Sentence examples for multiple transcription binding from inspiring English sources

In addition, multiple transcription binding sites are identified in the CNS2 region by DNA cross-species conservation analysis.

Genes are regulated by multiple transcription binding sites that interact with a specific combination of transcription factors.

The promoter composition of the genes is one of the major determinants of gene regulation including multiple transcription binding sites that interact with a specific combination of transcription factors (TF).

This observation has been corroborated by Kim et al., who further found in mouse embryonic stem cells that gene expression changes best correlate with multiple transcription factor binding, such that binding of a single transcription factor to any gene loci is infrequently associated with changes at the mRNA level[9].

It is important to note that this deletion removes multiple transcription factor binding sites, including the FUSE binding element known to be required for proper MYC expression [16].

This point was studied in detail in the case of the decidual prolactin gene, dPrl, where modifications after insertion provided multiple transcription factor binding sites that bind factors that interact with each other [ 206].

For every subset of promoters considered in the main text, we calculated the percentage of promoters having multiple transcription factor binding sites, and the percentage of binding sites localized in nucleosome [ 34].

Properties of the transcriptional machinery such as multiple transcription factor binding sites, synergy and cooperativity [ 37], and fractal kinetics [ 38] will contribute to sigmoidal gene regulation functions.

The conserved modules containing multiple transcription factor binding sites (Table 2 and Figures 3 and 4; Additional file 11 gives fasta sequences, list of binding sites and coordinates) are likely to play a role in regulation of expression of these genes, but this hypothesis must be experimentally verified.

We propose that SVAs have inserted preferentially into genic regions placing them in areas of the genome where they have the potential to affect transcription or post transcriptional regulation through several mechanisms such as methylation state, provision of multiple transcription factor binding sites or formation of DNA secondary structures.

Since not all cis-elements are known and transcription regulation most likely results from the presence and a combinational use of multiple transcription factor binding sites [21], computational identification of such sites can provide a rapid and cost-effective method for identifying groups of co-expressing genes with high success.