Sentence examples for multiple transcript variants from inspiring English sources

The majority of mammalian genes generate multiple transcript variants and protein isoforms through alternative transcription and/or alternative splicing, and the dynamic changes at the transcript/isoform level between non-oncogenic and cancer cells remain largely unexplored.

Alternative splicing (AS) is a common post-transcriptional process used by eukaryotic organisms to generate multiple transcript variants from a single gene [1].

Sprouty (SPRY) are inhibitors of receptor tyrosine kinase modulating tracheal branching in Drosophila and their alternative splicing results in multiple transcript variants (SPRY1, SPRY2, SPRY3, and SPRY4) [12,13,14], which are reported to downregulate the expression of epidermal growth factor receptor (EGFR).

Alternative splicing results in multiple transcript variants, including two forms that contain either 27 or 38 amino acids (PACAP27 and PACAP38).

Whenever multiple transcript variants exist, the most represented and/or the longest isoform was chosen.

Alternative splicing of this gene is known to produce multiple transcript variants.

The common sequences from genes with multiple mRNA transcript variants were used for PCR primer design.

Multiple different transcript variants were found for the human VDR.

However, there is often uncertainties in the choice of recognizable splice signals, resulting in a process termed alternative splicing [ 17], which enables the origination of multiple mRNA transcript variants from a single gene locus [ 67- 69].

It is estimated that 40 79% of human genes with multiple exons produce transcript variants [18].

Multiple alternatively spliced transcript variants of the RBMS3 gene that encode various isoforms have been found.