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These results suggest the presence of one QTL with pleiotropic effects on multiple traits or multiple QTL within the marker interval.
This method is as generally applicable as the method of maximum likelihood: to cases where designs are balanced or unbalanced, involving mixed effects and multiple traits or designs where random effects are correlated to each other.
However, due to the absence of crossovers in the major part of each chromosome it is unclear that if these QTLs represent pleiotropic QTL having effects on multiple traits or closely linked genes.
They will also enable marker-assisted selection for multiple traits or for specific genome regions.
Any workflow that might want to look for groups of nodes or edges that share multiple traits, or that explicitly do not share those traits.
However, its application to multiple traits or environments in crop populations, where both additive and non-additive genetic variation can be measured, raises some issues to be resolved.
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When reigning evolutionary theories were formulated in the 19th and 20th Centuries, non-Mendelian events like these that simultaneously affect multiple traits were unknown or ignored.
Also, integrating diverse phenotypic readouts facilitates genetic interaction screens [ 103], and Bayesian models have been shown especially useful for making use of multiple traits, gene-gene or gene-environment interactions in disease risk prediction [ 104].
However, this approach treats SNPs and traits as independent units, and overlooks relationships in which multiple SNPs jointly affect a single trait or multiple traits as well as pleiotropy, where one genetic locus influences multiple phenotypic traits.
The use of site-averages, single-variable proxies, or multiple traits will not remove this underlying signal or reconcile the inherent uncertainties from non-independent data, and would mask the true uncertainty in prediction error.
The list of genes falling in any QTL regions for single or multiple traits can be saved using the "Save" option on the viewing panel or "Left-clicking" the highlighted QTL region.
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