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The program also prepares the coefficients for the mixed model equations based on the statistical model for single and multiple trait analyses.
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Calus and Veerkamp [ 27] used simulated data to investigate the performance of three marker-based models in multiple-trait analyses.
Single-trait and multiple-trait analyses correspond to the solution of m×1 (1-dimensional) and m×t (two-dimensional) grids of GLS problems, respectively.
Secondly, GxE interactions were analysed as part of the multiple trait CIM analyses.
Finally, since we were including multiple traits in these analyses, we wanted to account for groups of correlated traits.
To better control for the analysis of multiple traits, each of the three experiments, were also analysed by multiple trait CIM (MT-CIM) [ 36, 37].
Although some of these QTL studies considered multiple traits, they were analysed separately thus neglecting possible genetic correlations between traits.
Quantitative trait analyses were performed using a multiple linear regression analysis with or without adjustments for related covariables.
The simplest approach to analyse multiple traits is to perform a series of single-trait analyses and then combine the results.
The estimates of heritability for deafness are roughly equivalent to those for the univariate analyses in Table 2. Similarly, there is no evidence in the multiple trait analysis for gender differences in the risk of hearing loss.
Chromosomal regions affecting multiple traits (multiple trait quantitative trait regions or MQR) in dairy cattle were detected using a method based on results from single trait analyses to detect quantitative trait loci (QTL).
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