Sentence examples for multiple toxicities and from inspiring English sources

[ 29] One of the best ways to prevent these dots from forming is to prevent excess substrates (table 3) which cause the multiple toxicities and the multiplicative effect of the A-FLIGHT toxicities associated with MS, IR, PD, and T2DM.

Therefore, in T2DM we should consider looking at the multiple toxicities and how they interact with each other to form "the whole disease" and return metabolic and redox homeostasis to the organism.

Four patients had multiple toxicities, and required UFT dose modification (one patient had grade 4 mucositis with grade 3 diarrhoea, one had grade 4 mucositis with grade 4 diarrhoea, one had grade 3 mucositis and grade 3 diarrhoea, and the fourth had grade 3 diarrhoea and grade 3 nausea).

Some patients had multiple toxicities and these are separately documented in this table Eleven of the 14 patients had baseline MRI scans obtained before the SABR treatment, and all patients had MRI obtained at follow-up visits as per the protocol guidelines.

Still, addressing multiple toxicities and allowing genotype-based adjustments of several anticancer agents in order to reduce the burden of therapy and simultaneously improve cure rates may be a proof-of-principle approach even though the subsequent statistical and biological identification of the most important treatment modifications will be challenging.

Dose reductions were instituted for mitomycin C in two patients (due to neutropenia), for cisplatin in four patients (due to impaired renal function from the start of chemotherapy in two cases and multiple toxicities in two cases) and for 5-FU in 12 patients (for reasons of stomatitis in seven, palmar-plantar syndrome in three, and diarrhoea and neutropenia in one case each).

Several overarching issues were identified that pertained to multiple agents; these included the importance of recognizing that carcinogenic agents can act through multiple toxicity pathways and mechanisms, including epigenetic mechanisms, oxidative stress, and immuno- and hormonal modulation.

Recent advances in cancer biology support the view that carcinogenic agents can act through multiple toxicity pathways and mechanisms, including both genetic and epigenetic changes.

The present study was focussed to optimize the safe application of ZnO-NPs by assessing multiple toxicity points and in vitro distribution in nanoparticle-exposed C. elegans.

Human exposure to benzene is associated with multiple toxicities affecting the hematological, hepatic, immunologic, and chromosomal functions and an increased risk of carcinogenesis.

If we view T2DM as a vascular disease initially with a later manifestation of hyperglycemia, we may be able to better understand and modify the multiple toxicities associated with insulin resistance, metabolic syndrome, prediabetes, overt T2DM, and accelerated atherosclerosis (atheroscleropathy).