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Among these species, salamanders can be thought of as the 'champions of regeneration' because they are tetrapod vertebrates that can completely regenerate multiple tissues, such as the lens, ventricle and limb, and partially regenerate their intestine and spinal cord ([3 5], two examples of salamander species are shown in Fig. 1a b).
Vesl-2 (Homer 2) is a post-synaptic adaptor protein that has been shown to be present in multiple tissues such as brain and heart.
Similarly, the CG4238 gene is derepressed in multiple tissues, such as endoderm, salivary gland and a subset of somatic mesoderm from stage 11 (supplementary material Fig. S10).
FFA has been demonstrated to be a critical factor for causing systemic insulin resistance in multiple tissues, such as liver and muscle.
Notch signaling regulates the maintenance, fate decision, and proliferation of progenitor cells in multiple tissues such as bone marrow and various neuronal tissues [ 17].
Low expression of the human homologs of Casc5, Ctage5, Pbk and Spag9 has been observed in multiple tissues, such that these are cancer testes-selective antigens and they may be subject to tolerance [ 32].
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Furthermore, our method may not be able to distinguish TF targets from other co-expressed non-target genes, although meta-analysis across multiple tissues reduces such a possibility.
In addition to liver, hepcidin is made by multiple other tissues such as kidney (hepcidin is present in thick ascending limb of the cortex and in connecting tubules), pancreatic beta cells, adipose tissue or heart (hepcidin is found at the intercalated disc area) [9] [12].
The RNAs used to generate the data were isolated from multiple soybean tissues, such as leaves and roots.
Adipose-derived stem cells (ADSCs) are multipotent cells that can differentiate into cells of multiple tissue lineages, such as osteocytes, chondrocytes, adipocytes, or neuronal cells.
EV-OCT is also able to image intra coronary atherosclerotic plaques and can identify multiple tissue structures such as fibrous cap, intra-plaque lipid deposition, and intra-plaque calcification nodules [ 9].
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