The complex effects of drugs at multiple receptor subtypes in multiple tissues have made it difficult to isolate the relative contributions of GPCR regulation, ligand binding, effector coupling, drug metabolism, and cellular downregulation machinery.
Due to their diverse differentiation potentials, the relative ease of their isolation from multiple tissues, the fact that they can be expanded and multiplied in vitro, and their immunomodulatory properties, MSCs are regarded as a promising tool for clinical applications.
Sequencing transcripts from multiple tissues and subspecies netted a greater overall coverage of the M. sativa transcriptome (relative to M. truncatula), than either single tissue analyses from multiple alfalfa cultivars (M. sativa ssp. sativa, M. sativa ssp. caerulea, and M. sativa ssp. falcata [ 29]) or from multiple tissue samples from a single alfalfa cultivar [ 32].
In addition, multiple tissues were harvested from NiV-challenged monkeys at the time of necropsy and the relative quantity of NiV RNA was measured.
The Gene Sorter ranks 20,161 human genes based on their difference in tissue-specific expression levels relative to a selected gene, which was ranked at number 1, using data from multiple tissues including fetal brain, whole brain, amygdala, thymus, bone marrow, CD4+ peripheral blood cells, adipocyte, pancreatic isles, heart, lung, kidney, liver, ovary and testes.
These changes can occur synchronously across multiple tissues and organs.
These studies have identified HACNSs specifically marked in human embryonic tissues relative to other species.
It is expressed in multiple tissues and at different stages of development.
This study provides a comprehensive analysis of circadian metabolic profiles across multiple tissues.
Secreted signaling molecules have a myriad of roles during development and adult homeostasis in multiple tissues.
