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SIRT3 is transcriptionally upregulated in multiple tissues during nutrient stresses such as dietary restriction and fasting, but the molecular mechanism of this induction is unclear.
RESULTS: We document dorsal closure in living embryos to show that mutations in nonmuscle myosin II (encoded by zipper; zip/MyoII) disrupt the integrity of multiple tissues during closure.
Adrenomedullin (ADM) is a peptide which can act as a hormone and is produced by multiple tissues during physiologic and infectious stress with varying physiological functions, including vasodilatory, anti-inflammatory and antimicrobial activity, which is further enhanced by its regulation and modulation of complement activity [7].
The objective of our study was to try to determine a putative mechanism of how gene expression is coordinated across multiple tissues during the pregnancy to lactation transition.
To develop a clearer picture of how gene expression is coordinated across multiple tissues during the pregnancy to lactation transition, total RNA was isolated from mammary, liver and adipose tissues collected from rat dams (n = 5) on day 20 of pregnancy and day 1 of lactation, and gene expression was measured using Affymetrix GeneChips.
AP2 genes are generally transcribed in multiple tissues during development.
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Voisin, M. B., Probstl, D. & Nourshargh, S. Venular basement membranes ubiquitously express matrix protein low-expression regions: characterization in multiple tissues and remodeling during inflammation.
Jmjd6 has recently been shown to hydroxylate RNA splicing factors and is known to be essential for the differentiation of multiple tissues and cells during embryogenesis.
The epithelial to mesenchymal transition (EMT) plays a crucial role in the differentiation of multiple tissues and organs during embryogenesis [ 17].
Mesenchymal epithelial transition is also a critical process for the formation of the body plan and in the differentiation of multiple tissues and organs during embryonic development (Davies, 1996; Nakaya et al, 2004).
A total of 32 regulators are characteristically expressed in multiple tissues undergoing cell differentiation events during seed development, also during the shift from germination to seedling establishment as well during the transition from vegetative to generative development (cluster group 4, Figure 3; Additional file 3).
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