Sentence examples for multiple tissue lineages from inspiring English sources

Adipose-derived stem cells (ADSCs) are multipotent cells that can differentiate into cells of multiple tissue lineages, such as osteocytes, chondrocytes, adipocytes, or neuronal cells.

Our goal was to explore the genesis of Pten-deficient malignancies in multiple tissue lineages of the adult mouse.

These hiPSCs have the characteristics of hESCs, including prolonged growth in culture and differentiation to multiple tissue lineages.

Together these results suggest that Bcor plays a role in differentiation of multiple tissue lineages during early embryonic development.

Although the multiple tumors that occurred simultaneously in the Pten-deficient mice may have complicated the monitoring of tumor formation compared to other mouse models that have used Pten ablation in a tissue-specific manner, our study is able to provide knowledge that will help an understanding of Pten tumor suppressor functional requirements in multiple tissue lineages and cells.

Henceforth, these ASC have the potential to differentiate towards multiple tissue lineages, produce a large variety of growth factors and present immunomodulatory properties [ 1].

Mesenchymal stem cells are multipotent stem cells that give rise to multiple connective tissue lineages, including cartilage and bone.

This suggests that over-expression of ATF3 results in fundamental alterations in the differentiation status of the affected tumor cells, including expression of markers characteristic of multiple tissues and epithelial lineages.

Finally, mex3-1 RNAi) worms have impaired contribution to tissue turnover, as evidenced by drastically reduced production of lineage-restricted neoblast descendants and diminished cell addition towards multiple tissue types, in addition to the epithelium.

In mice, heterozygous PAX3 mutations result in defects in multiple tissues derived from the neural crest lineage including the patchy hypopigmentation in skin and fur, whereas homozygosity leads to prenatal or perinatal lethality.

Interestingly, during development of the central nervous system, both glial and neuronal cell lineages were shown to emerge from a common progenitor that expresses proteolipid protein 21, a major myelin component, suggesting that blurring of progenitor and lineage phenotypes may occur within multiple tissues.