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miR-21 is broadly expressed in multiple tissue, expression in the heart cells is developmental and age-dependent [ 36], there is difference in expression between infracted regions and border zone [ 36] as well as in cell type (cardiomyocytes, fibroblasts, etc).
The Multiple Tissue Expression Array revealed that some cancer cell lines express PDXP.
But more sensitive methods of mRNA detection, including RT-PCR [14] and multiple tissue expression arrays [15], revealed sAC mRNA to be universally expressed.
In this study, it was shown that brain was the organ that expressed the most abundant ANP32A by human multiple tissue expression (MTE) array.
Multiple tissue expression data from day 3 of the fifth instar showed that 1,403 of the 2,436 induced genes have multiple tissue expression, indicating that almost all of the silkworm tissues were affected by the infection [19].
By applying BEEM to the TF binding motif gene sets and multiple tissue expression data set, we assigned a p-value to each gene set.
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Most of the SUN genes were expressed at low levels across multiple tissues; expression was similar within tissue types, regardless of developmental stage.
Application of BEEM to the multiple tissues expression data set discovered of 11 regulatory motifs that regulate the diverse transcriptomes.
The microarray data of multiple tissues expression of day 3 of the fifth instar were downloaded from the silkworm genome database (http://www.silkdb.org/microarray/download.html) (10,393 active transcripts) [excel].
Building on improved computational methods to correct such opposition, Chan et al. [ 16] compared multiple tissue-expression datasets across five vertebrate species: human, mouse, chicken, frog and pufferfish, and found the evidence of conserved expression in more than a third of unique orthologous genes.
Incorporation of multiple tissue gene expression data into the analysis demonstrated an association of tissue specificity with changes of gene expression from myoblast to myotube.
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