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Lmna-/ mice appear normal at birth but become runted as early as 2 weeks of age and develop multiple tissue defects that mimic some aspects of human laminopathies.
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We present our experience with the versatile design of the distally based saphenous neurocutaneous perforator flap to provide coverage of complex post-traumatic medial malleolar defects by harvesting multiple tissue components in various combinations.
In addition to these pigmentation defects and tumors of the peripheral nervous system (PNS), NF1 patients demonstrate highly diversified clinical features with multiple tissue types affected.
All immune-localisation experiments were performed on multiple tissue sections.
Biomaterials are increasingly used in the repair of tissue defects.
Finally, cartilage strands were engineered, bioprinted and then implanted into ex-vivo osteochondral tissue defects and were able to further undergo remodeling within the host tissue.
Although tissue transplantation remains to be the preferred therapy for tissue defects, the shortage of donors is a major obstacle that limits its application.
Third-place winner was the Stem Cell Therapy for Soft Tissue Defects team, led by Nicholas Gill.
Emphasis was placed on soft tissue reconstruction with the closure of soft tissue defects with well-perfused healthy tissue.
Using multiple tissue Northern blots from over 50 different tissues, PSGR expression was restricted to human prostate tissues.
Soft tissue defects require the use of muscle flaps frequently.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com