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We highlight current strategies to protect and repair brain tissue with the promise to provide longer therapeutic windows, preservation of multiple tissue compartments and improved clinical success.
Dietary and endogenous Cr enters systemic circulation and is actively transported into multiple tissue compartments by a transmembrane Na+ and Cl− -dependent creatine transporter (CrT), encoded by the SLC6A8 gene [21].
We observed similar results in the lung (not shown), suggesting CD28 regulates inflammation in multiple tissue compartments.
Simulations of the kind presented here can be expanded to incorporate additional proteins and multiple tissue compartments to model drug pharmacokinetics and pharmacodynamics.
To directly explore the possible regulatory difference of p53 in vivo, B6 mice was either untreated or treated with 6 Gray of X-irradiation and immunostained for p53 protein in multiple tissue compartments.
Important new features of this model include: (i) the simulation of AR in multiple tissue compartments (i.e., brain, liver, and gonad); (ii) AR binding and its effects upon the HPG axis; and (iii) free androgen effects on brain AR concentration.
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For example, multiple tissue compartment areas can be filled with different chemoattractant solutions and concentrations to understand in a realistic environment the balance of hydrodynamic shear forces, rolling, adhesion, and subsequent migration.
IGFBP-4 mRNA was detected in multiple uterine tissue compartments.
However, conducting several independent studies to consider multiple endpoints and/or tissue compartments is resource intensive.
In view of studies demonstrating that CREB contributes to proliferation and differentiation of different cell types in multiple non-GI tissue compartments, we deleted CREB in the intestine using a Tamoxifen-inducible CRE-mediated intestine-specific crebKO mice line.
Limbs consist of multiple tissue types in different compartments, all of which work together to carry out complex limb movements and functions.
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multiple tissue contexts
multiple tissue models
multiple tissue cores
multiple dendritic compartments
multiple organ compartments
multiple tissue interfaces
multiple tissue interactions
multiple tissue samples
multiple tissue data
multiple tissue lineages
multiple retroperitoneal compartments
multiple tissue layers
multiple prespore compartments
multiple tissue sections
multiple tissue characteristics
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