The high prevalence of isolates with multiple pfmdr1 copies found in western Cambodia near the Thai border, where artesunate mefloquine therapy failures occur, contrasts with isolates from eastern Cambodia, where this combination therapy remains highly effective.
The use of flow cytometry allows for single cell, quantitative, and fast assessments of multiple outcomes affecting anti-tumor therapy failure.
Altered expression of BUB1 is associated with therapy failure and death in patients with multiple types of cancer [ 19].
Mechanisms underlying cancer therapy failure and treatment resistance are summarized.
"Although small, this study highlights the potential for multiple therapies such as expressive arts therapy incorporating movement and physical therapy focusing on the pelvic floor".
Antibiotic therapy failure correlates with bacterial biofilms.
ARV resistance impairs the response to therapy in patients with transmitted resistance, unsuccessful initial ARV therapy and multiple virological failures.
Similarly, in critically ill patients with multiple organ failure, rHuEPO therapy will also stimulate erythropoiesis.
A few studies, primarily in cardiac surgery or trauma patients and in long-term ventilator weaning centres, have identified similar predictors of poor outcome including age [ 5, 12, 16, 19, 28- 30], inotrope requirements or nosocomial sepsis [ 5, 16], immunosuppression [ 16], need for renal replacement therapy [ 10, 16], and multiple organ failures [ 31].
Finally, rifabutin-based therapies have achieved promising results and are even effective in patients with multiple failures or multiple antibiotic resistance.
