Family-based designs also have substantial benefits in terms of accounting for multiple-hypothesis testing, especially when hundreds of thousands of genetic markers are tested simultaneously, because they contain both within- and between-family information [ 35].
Furthermore, predictions of the engineering performance of aged components are prone to large errors when the service lifetimes are much greater than the duration of laboratory aging tests, especially when multiple degradation mechanisms contribute to the overall aging.
Individuals having a single positive autoantibody (insulin, GAD65, IA-2, or ZnT8 autoantibodies) are at low risk for progression to diabetes, whereas individuals expressing two or more positive autoantibodies, especially on multiple tests over time, are at very high risk for progression to diabetes (9, 10).
Training was more effective for improving the accurate interpretation of more complex results, e.g. results with faint test lines or for multiple test lines, and especially for improving interpretation skills of inexperienced participants.
[Abstract available: www.informaworld.com/smpp/content∼db=all∼content=a911582565] In this study, Chang and colleagues document and characterize the "testing effect," the impact of taking tests, especially those with multiple-choice questions, on students' learning.
Multiple tests increase the possibility of chance associations, especially when conducting a non-replicated study.
Due to the relatively small sample sizes of the studied groups, the association analysis of two-locus genotype combinations was underpowered, especially after Bonferroni adjustment for multiple tests.
Multiple tests are available for the monitoring of antiplatelet therapy, especially aspirin and clopidogrel.
Overall, our findings suggest that confidence-weighted multiple-choice tests can be particularly useful as practice tests, especially to the extent that questions on the subsequent test (the one that matters or matters more) are different questions.
The major difficulty with studies using large numbers of tests, especially using the new high density SNP panels, is setting an appropriate correction for multiple testing.
