FTO-SNP rs1121980 rendered the lowest nominal p-value of 1.13×10−7; this SNP was the only SNP that survived correction for multiple testing (corrected p = 0.0494; Table 1).
The multiple testing corrected P-values (Benjamini correction) are reported.
We identified four regions which showed an excess of deletions in controls, but these regions did not remain significant after correction for multiple testing (corrected P > 0.4).
We therefore performed an FDR correction using "p.adjust" and provided the list of multiple testing corrected p-values in the additional files (Additional file 1).
This p-value would correspond to a multiple test corrected p≈0.05.
The negative log of the multiple testing corrected best p-value is a score for the subset pair.
coeff: Spearman correlation coefficient, adj.p.values: multiple testing corrected FDR.
Benjamini-Hochberg multiple test corrected p values are shown only.
Significant difference (P <0.05) was determined by ANOVA or Bonferroni post hoc tests (multiple testing corrected).
Q-values are the multiple testing corrected P-values [ 60, 61].
