Heininga, V. E., Oldehinkel, A. J., Veenstra, R. & Nederhof, E. I just ran a thousand analyses: benefits of multiple testing in understanding equivocal evidence on gene-environment interactions.
The score was not significantly associated with the number of non-silent mutations (Supplementary Figure 3), germline single nucleotide polymorphisms (SNPs), or somatic mutations in individual genes (after adjusting for multiple testing in the cases of SNPs and mutations).
Importance sampling method of correction for multiple testing in affected sib-pair linkage analysis.. BMC genetics.
Importance sampling method of correction for multiple testing in affected sib-pair linkage analysis.
Other directions include developing an optimal way to make corrections for multiple testing in settings where there are potentially more covariates (SNPs) than observations.
However, it is important to note that many of these improvements were lost during multiple testing in the Klooker et al. trial.
No consensus exists regarding the best method to correct for multiple testing in association studies.
These results are highly significant even when adjusting for multiple testing in MAPPFinder (Adjusted p-value).
A permutation test was used to address the issue of multiple testing in mtSNP association tests.
However, none of these associations survived correction for multiple testing in the two African American samples [18], [28].
FAM-MDR adequately deals with multiple testing in epistasis screens and is in contrast rather conservative, by construction.
