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Multiple testing between single arms in a three-armed trial is handeled by the closed testing procedure: If a difference between all three arms is assessed by a global test on significance level 5%, it is possible to use the same level for the three two group comparisons.
Thereby Bonferroni-Holm adjustments were set to account for multiple testing between the groups.
For subsequent post hoc tests, adjustments for multiple testing between subgroups (i.e. genotypes) were made with Bonferroni correction.
There were no significant associations (all P-values were greater than.05 after correction for multiple testing) between MBL2 genotypes and any of our predefined analyses.
For both single SNP- and haplotype-based association analyses, P values were calculated by running 10,000 permutations using the max (T) procedure to correct for multiple testing between SNPs or haplotypes by each BACS-J subtest.
Permutation P-values, P (perm), were adjusted for multiple testing between SNPs by each BACS-J subtest P-values < 0.0083 (0.05/6) were considered as statistically significant to correct for the number of BACS-J subtests.
Similar(49)
The solid state laser was mounted to a tactical military vehicle and carried out multiple tests between Nov. 18 and Dec. 10 at the Army's White Sands Missile Range in New Mexico.
Comparison of different groups was carried out by using the analysis of variance test with a Bonferroni correction for multiple tests between the different groups.
We found a significant association (p-value < 8.4e-4, Bonferroni corrected for multiple tests) between MC1R and RH2 (Fig. 4; we excluded the OPN1sws2 and OPN1lw opsins due to insufficient sampling size for implementing the association tests (≤15)).
Differences across motifs and types of SSRs were tested by comparing within (including correction for multiple testing) and between the Hymenoptera and Diptera using a two-tailed Mann–Whitney U test.
The number of significantly differentially expressed genes (false discovery rate (FDR) <0.05, corrected for multiple testing) varied between 3657 (UKF-NB-3 versus UKF-NB-3rNutlin10 μ M) and 6375 (UKF-NB-3 versus UKF-NB-3rCDDP) being less than a twofold difference.
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