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None of the reported P values were corrected for multiple testing; applying a Benjamini-Hochberg approach to correct for 21 SNPs and 3 measurements, a P value of <0.0024 would be significant (4).
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Further compounding such errors in interpretation of hypothesis tests is that all such tests are treated as independent with no correction for multiple testing applied.
Potential allelic segregation distortion in the 2n gamete population was tested at each marker using χ-analysis (0.05 probability threshold) with the Bonferroni correction for multiple testing applied (Additional file 2).
As ordinal data, rank-based methods are used for all inferential statistics with a Bonferroni correction for multiple tests applied as appropriate (see online supplementary table S3 for details).
On the other hand, deployment of more accurate imaging techniques earlier in the care pathway could reduce the patient inconvenience, cost and anxiety associated with diagnostic algorithms comprising multiple tests applied sequentially.
HWE and pairwise FST tests were corrected for multiple testing by applying a Bonferroni correction.
Statistical significance of Mantel test was corrected a posteriori for multiple testing by applying Bonferroni correction.
Alpha-levels were adjusted for multiple testing by applying a Bonferroni correction.
In these analyses, we controlled for multiple testing by applying a Bonferroni correction.
P-values were corrected for multiple testing by applying "False Discovery Rate" (FDR) (Benjamini and Hochberg 1995).
To correct for multiple testing we applied the Bonferroni correction (P < 1.7 × 10−7, corresponding to 0.05/number of analyzed SNPs).
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