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Furthermore, a multiple testing analysis was not applied to genotypic differences in relation to various measures of kidney function.
Limitations of the study include small size of the sample, small number of C/C genotype patients, and a lack of multiple testing analysis of genotypic differences in various measures of kidney function.
MZ was responsible for multiple testing analysis.
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Multi-experiment viewer v4.4 (Mev) software was used for the Significance Analysis of Microarray (SAM) method, a multiple testing statistical analysis, to identify genes that were differentially expressed in response to SSR.
Multiple testing correction analysis was not applied, and all unassigned reads were ignored.
The authors thank Dr. Sabina Bijlsma (TNO, the Netherlands) for help with multiple testing correction analysis.
Analysing the many possible combinations would require very large numbers to allow correction for multiple testing, an analysis beyond the scope of this study.
The false discovery rate (FDR) was used to determine the threshold of P value in multiple test and analysis.
FDR (false discovery rate) was used to determine the threshold of P-value in multiple test and analysis.
FDR is a method to determine the appropriate threshold of the P value in multiple test and analysis.
In addition to the P-value, false discovery rate (FDR) was used in DGE to determine the threshold of P-value in multiple test and analysis [ 66].
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