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This is followed by multiple testing adjustments, and mean levels of methylations were compared across phenotype categories while adjusting for the known and computed confounders in the form of PCs.
No multiple testing adjustments were applied.
All the DEGs were obtained after multiple testing adjustments (5% FDR).
Multiple testing adjustments were applied separately to each trait, therefore only controlling for multiple testing within each trait.
Multiple testing adjustments were not performed because the study is in essence replication of previous studies regarding individual SNPs (not discovery) (Table 5).
Transmission disequilibrium test analysis, followed by multiple testing adjustments for all 66 SNPs genotyped, revealed significant genetic association for the SNP rs1641021.
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The Hochberg procedure was used for multiple testing adjustment, and adjusted p < 0.05 was used as the significant criterion.
A multiple testing adjustment [ 125] was performed on the t-statistics of each contrast to adjust the false discovery rate, and on the 1-way ANOVA F-statistics.
The Bonferroni method was used for multiple testing adjustment of the p-values obtained from the 18 paired t-tests conducted; adjusted p-values of p ≤ 0.05 can be interpreted as statistically significant test results.
Stars indicate significant enrichment (One-way ANOVA, P < 0.05; Multiple testing adjustment, FDR) in the different fumigation years.
This reduction in the number of variables increased the power to detect significant associations between mood state and chronobiological variables secondary to the more favorable multiple testing adjustment profile.
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