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The parameter "relative fecundity" is derived form the other 3 reproductive parameters [ 5]. c Data of FVB strain was taken from Silver's Mouse Genetics textbook [ 5]. a Number of clones resulting from a regression analysis with false discovery rate (FDR) control performed with the multiple test tool Pomelo (accessible at http://pomelo2.bioinfo.cnio.es/).
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With the improved Conversion Lift tool, advertisers can compare multiple test and control groups.
Using hypergeometric test, the top 10 groups of protein coding genes from each CNV subgroup that are targets for miRNA were generated by this tool and ranked by adjP (p value adjusted by multiple test adjustment).
The transcription factor affinity prediction tool TRAP [ 55] (multiple sequences) was implemented with the 904 TRANSFAC [ 56] motifs (transfac_2010.1 vertebrates), background model of human promoters, and Benjamini-Hochberg multiple test correction.
This Enrichment of Gene Ontology (GO) category was tested with a Hypergeometric test followed by the Benjamini Hochberg correction for multiple testing using the analysis tool GOToolBox [ 60].
Systematic multiple testing with statistics and classification tools was programmed in perl using subgroups of patients and subgroups of genes.
Key statistical and multiple testing correction methods used by each tool are shown in Table S8.
Prior to the evaluation of somatic sets, analysis of GO biological process terms in the GWAS permutation P values rank did not show any significant asymmetry using the Gene Set Enrichment Analysis (GSEA) tool [31] with multiple testing correction by the false discovery rate (FDR) approach [32].
GO-2D can also output all the observed p values, which can be used for other complicated multiple tests correction by many other existing tools such as the program for Storey's Q value [ 17]. (6) Results: GO-2D allows users to save the results for detailed examination of the identified modules.
Benjamini and Hochberg false discovery rates were also reported by the tool to account for multiple testing.
For all tools, p-values were corrected for multiple testing using the False Discovery Rate (FDR) [ 18], and corrected p-values < 0.05 were considered significant.
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CEO of Professional Science Editing for Scientists @ prosciediting.com