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Among aryl amines, 13 out of 57 compounds with multiple test results were discordant (23%).
Agreement beyond chance between assessors was calculated using kappa's coefficient for multiple observers and multiple test results.
Multiple test results for a single specimen may have also contributed to reporting irregularities.
However, multiple test results increase time for data processing.
GWATCH offers a number of "features" that allow automated analysis and visualization of multiple test results, rapid discovery, replication and data release of unabridged association results (Table 1).
However, access to multiple test results supports the creation of predictors that are more complex and hopefully more accurate, since they are based on the integrated results from more parameters.
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Given the independence of our data sets, we chose to address the problem of combining multiple testing results by using Fisher's combination test.
To account for multiple testing, results with p < 0.005 were considered to be significant.
Due to multiple testing, results with p < 0.0005 were considered to be significant.
This Bonferroni correction for multiple testing results in a per-family error rate (PFER) of one [ 40].
This is a stringent cut-off since using a Bonferroni correction for multiple testing results in: 0.05/20,677 > 10-6.
More suggestions(15)
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