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Correcting for multiple testing, the program computes q-values based on the posterior probability for each locus, and we considered loci with q < 0.05 consistently in three independent runs significant outliers.
a P = 0.012 after correcting the P-value for multiple testing by Haploview program using 10,000 permutations.
The p-values of all tests were corrected for multiple testing using the program Q-value [ 38] with a FDR of 10%, acknowledging that the multiple tests conducted are highly intercorrelated and a stricter correction would therefore be overly conservative [ 39, 40].
Significantly up- and downregulated genes are obtained by a conventional t-test with multiple test adjustment as implemented in the Babelomics program [ 89].
A post hoc Waller Duncan multiple test range was performed which considered a 5% significant level using SPSS ver. 11.5 computer software program.
Multiple test adjustments were computed using the false discovery rate method [12], [13] as implemented in the q-value program [13].
Prior studies have shown that formalized elective curricula [ 11, 12] or inclusion of elective specific multiple-choice testing program [ 13] improves resident performance on standardized tests of medical knowledge.
The TaintDroid system cannot provide any path information implemented in the software testing process and cannot distinguish if the implementation of the multiple tests have the same program path, thus leading to a very large blindness.
After applying the chi-square test and Benjamini-Hochberg multiple testing corrections using R program among three samples simultaneously, we identified 2,858 genes as reliable DEGs in at least two samples (assigned as either DEGs) regardless of fold change (Additional file 6).
Analysis for allelic and haplotypic associations was performed with the UNPHASED program and multiple testing was corrected using permutation.
Analysis for allelic and haplotypic associations was performed with the UNPHASED program and multiple testing was corrected using false discovery rates.
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