Sentence examples for multiple targets of action from inspiring English sources
The widespread effects of citral suggest multiple targets of action.
Although new questions about the relevance of multiple targets of action for exogenous compounds are deeply in discussion, the original contributions that depict novel insights into basic and clinical aspects with perspectives on medical application are welcome.
Plant extracts contain a great diversity of bioactive compounds with multiple targets and mechanisms of action.
Some have been shown to act at singular targets while others act at multiple targets through nonspecific action [ 42].
Targets of action were identified based on EPA cpad.
4 6 The currently approved bDMARDs target multiple mechanisms of action (MOAs), including T cell costimulation (abatacept) and tumour necrosis factor-α inhibition (eg, adalimumab), the most widely used agents.
OVs are cytotoxic and target cancers via multiple mechanisms of action while at the same time exploiting validated genetic pathways known to be dysregulated in many cancers.
The lack of success of Aβ targeting therapies suggest that a single-pronged approach to the treatment of AD may be insufficient and has prompted an increased focus on the development of alternative methods that engage multiple mechanisms of action and target other downstream pathways such as synaptogenesis (Schubert and Maher, 2012).
Moreover, mechanistic data support the possibility that multiple modes of action with different targets within the developing heart may be operant in eliciting cardiac malformations, consistent with the reported association between TCE and overall cardiac malformations in the absence of a strong association with any particular type of defect.
This can be explained by the multiple mechanism of action of these compounds on several targets with the consequent therapeutical efficacy.
The combination of herbs that have different pharmacological activities may have better lipid-lowering effects than their individual ingredients or even comparable to single drugs probably contributed to their actions of multiple targets.
